Bergmann, A., Floyd, K., Key, M., Dameron, C., Rees, K.C., Thornton, L.B., Whitehead, C.D., Hamza, I., Dou, Z*., 2020, “Toxoplasma gondii requires its plant-like heme biosynthesis pathway for infection.” PLOS Pathogens, 16(5): e1008499. ( *, corresponding author)
McDonald, C.#, Smith, D.#, Di Cristina, M., Kannan, G., Dou, Z.#,*, and Carruthers, V. B.* 2020, “Toxoplasma Cathepsin Protease B and Aspartyl Protease 1 are dispensable for endolysosomal protein digestion.” mSphere, 2020, 5(1): e00869-19 (#, first author; *, corresponding author)
Key, M., Bergmann, A., Micchelli, C., Thornton, L.B., Millard, S., and Dou, Z.* 2020, “Determination of Chemical Inhibitor Efficiency against Intracellular Toxoplasma gondii Growth Using a Luciferase-Based Growth Assay.”Journal of Visualized Experiments, (158), e60985, doi:10.3791/60985 (*, corresponding author)
Thornton, L.B., Teehan, P., Floyd, K., Cochrane, C., Bergmann, A., Riegel, B., Stasic, A.J., Di Cristina, M., Moreno, S.N.J., Dou, Z.* 2019, “An ortholog of P. falciparum chloroquine resistance transporter (PfCRT) plays a key role in maintaining the integrity of the endolysosomal system in Toxoplasma gondii to facilitate host invasion.” PLOS Pathogens, 15(6): e1007775. (Featured research article; *, corresponding author)
Di Cristina, M., Dou, Z., Lunghi, M., Kannan, G., Huynh, M.H., McGovern, O., Schultz, T., Schultz, A., Miller, A., Hayes, B., van der Linden, W., Emiliani, C., Bogyo, M., Besteiro, S., Coppens, I., Carruthers, V.B., 2017, “Toxoplasma depends on lysosomal consumption of autophagosomes for persistent infection”, Nature Microbiology, 2, 17096
Cai, F., Dou, Z., Bernstein, S.L., Leverenz, R., Williams, E.B., Heinhorst, S., Shively, J.M., Cannon, G.C., and Kerfeld, C.A., 2014, “Advances in understanding carboxysome assembly in Prochlorococcus and Synechococcus implicate CsoS2 as a critical component”, Life, 5(2): 1141-71
Dou, Z., McGovern, O., Di Cristina, M., and Carruthers, V.B., 2014, “Toxoplasma gondii ingests and digests host cytosolic proteins”, mBio, 5(4): e01188-14 (Highlighted by a spotlight article in Trends in Parasitology)
Warring, S., Dou, Z., Carruthers, V.B., McFadden, G., and van Dooren, G., 2014, “Characterization of the Chloroquine Resistance Transporter homologue in Toxoplasma gondii”, Eukaryotic Cell, 13(11): 1360-70 (cover article)
Liu, J., Pace, D., Dou, Z., Guidot, D., Carruthers, V.B., and Moreno, N.J., 2014, “A Vacuolar-H+-Pyrophosphatase (TgVP1) is Required for Microneme Secretion, Host Cell Invasion, and Extracellular Survival of Toxoplasma gondii”, Mol Microbiol, 93(4):698-712
Dou, Z., Carruthers, V.B., 2013, TgCPL peptidase. For Handbook of Proteolytic Enzymes, Third Edition. Elsevier Academic Press
Dou, , Coppens, I., and Carruthers, V.B., 2013, “Non-canonical maturation of two papain-family proteases in Toxoplasma gondii”, J Biol Chem, 288:3523-34, (cover article)
Saouros, S.*, Dou, Z.*, Henry, M., Simpson, P., Carruthers, V.B., and Matthews, S., 2012, “Inhibition of SUB1 from Toxoplasma gondii by MIC5 via a mechanism similar to subtilisin prodomains”, J Biol Chem, 287:36029-40, (*co-first authors)
Dou, and Carruthers, V.B., 2011, “Cathepsin proteases in Toxoplasma gondii”, Cysteine Proteases of Pathogenic Organisms, Adv Exp Med Biol, 712:49-61.
Iancu, C.V., Morris, D.M., Dou, Z., Heinhorst, S., Cannon, G.C., and Jensen, G.J., 2010, “Organization, structure, and assembly of α-carboxysomes determined by electron cryotomography of intact cells”, J Mol Biol, 396:105-17
Toxoplasma Research in the Dou Lab 